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Controlling CRISPR

As our understanding of CRISPR technology grows, the extraordinary potential of this gene-editing system in the realm of therapeutic development comes closer and closer to realization. However, ownership of the intellectual property (IP) behind this technology is set to spark a protracted patent feud between...
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CRISPR Chain Reaction

A rare mosaic female fly, with a lighter left half mutated by MCR and a wild-type darker right half. A new genetic-editing technique based on integrating CRISPR/Cas9 technology into a Drosophila melanogaster genome can make homozygous mutants in half the time it would take using...
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A CRISPR Solution to ‘Bubble Boy’ Disease?

They named him Phoenix because he was born five weeks early while his parents were on vacation, and spent his first few weeks in an incubator. Kristen and Patrick Wilkinson thought they knew exactly which ashes their son might soon rise from. But when they...
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Building a genomic GPS with CRISPR

A new “app” for finding and mapping chromosomal loci using multicolored versions of CRISPR/Cas9, one of the hottest tools in biomedical research today, has been developed by scientists at UMass Medical School. This labeling system could be a key to understanding the spatial and temporal...
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Scientists Call for a Summit on Gene-Edited Babies

A group of senior American scientists and ethics experts is calling for debate on the gene-engineering of humans, warning that technology able to change the DNA of future generations is now “imminent.” In policy recommendations published today in the journal Science, eighteen researchers, including two...
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Biologists devise invasion plan for mutations

Biologists devise invasion plan for mutations On 28 December 2014, Valentino Gantz and Ethan Bier checked on the fruit flies that had just hatched in their lab at the University of California (UC), San Diego. By the classic rules of Mendelian genetics, only one out...
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