CRISPR, crispr genome editing system

CRISPR, the new genome-editing tool, has already saved thousands of lives — but chances are you won’t meet any of the survivors. That’s because they’re lab mice. Scientists have been using dramatically fewer mice for each experiment since the advent of the groundbreaking technology. CRISPR,...

Once you’ve carried out CRISPR to generate mutations in your cells of interest, the next step is to identify those cells that have been successfully edited. Then, you can generate clonal populations of these cells, get on with the job of investigating the effect of...

MIT, Broad scientists overcome key The following is adapted from a press release issued today by the Broad Institute. Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have engineered changes to the revolutionary CRISPR-Cas9 genome...

The picture shows an edited plant on the right which is shorter and has an altered pod structure. The wildtype plant is on the left. Credit: The John Innes Centre  CRISPR gene-editing is allowing rapid scientific advances in many fields, including human health and now...

More than ever, we can view the genomes of humans and other organisms as drafts—not final and canonical texts, but rough copies to be tweaked and refined. Although scientists have been able to edit genomes for many decades, their tools were often cumbersome to work...

Have you heard of CRISPR? Maybe you’ve heard the full term: clustered regularly interspaced short palindromic repeats–or maybe not. If you haven’t, I’m sure you’ll start hearing the snack-sounding acronym soon. It’s some revolutionary stuff. Equal parts thrilling and terrifying, it’s the most powerful genome...

Few sectors of the global economy are more hooked on gene modification technology than agriculture. Food powerhouses like the U.S., Brazil and Argentina now grow genetically modified (GM) crops on 40, 23 and 13 percent, respectively, of their arable land, and one in five farmable...

The new CRISPR as a technology only really came into the public spotlight last year. But already dozens, if not hundreds, of Chinese research hubs are using the technique on a range of animals. CRISPR research is being supported in China via grants from the...

SOURCE: JOHN GOODE/FLICKR You may have noticed Vertex Pharmaceuticals (NASDAQ:VRTX) just inked a $105 million deal with gene editing pioneer CRISPR Therapeutics with a potential value of $2.6 billion. Since its humble beginnings in 1989 Vertex has posted an annual loss in all but one year...

The genome editing technique known as CRISPR-Cas9 has taken the biology world by storm. Initially it was primarily used to knock-out (literally, to make inoperative) specific genes, however, scientists have now figured out how to use the system to knock-in genes as well as edit the...