Month: June 2015

The CRISPR gene-editing system just got even better: a new light-activated Cas9 nuclease could offer researchers greater spatial and temporal control over the RNA-guided nuclease activity, according to a study published today (June 15) in Nature Biotechnology. “This is an effective new system for extremely...

Study shows that CRISPR-Cas 9 genome editing can be perfectly safe in mice. With so much being written on why we should, or shouldn’t, employ CRISPR for germline editing, a new study published in Nature Methods has shown that some of those safety concerns might...

The gene editing technology, CRISPR/Cas9, is six times more effective than other techniques at targeting specific DNA sequences in zebrafish, according to a new study from the National Human Genome Research Institute (NHGRI) and published in Genome Research. This discovery, which also demonstrated that the...

I work on CRISPR.  I had previously worked with the older technologies mentioned in the podcast (which I thought was a pretty good description of CRISPR to non-scientists). Honestly the potential benefits of CRISPR far out weight the dangers, in my opinion.  CRISPR should allow...

Illustration by Sébastien Thibault Three years ago, Bruce Conklin came across a method that made him change the course of his lab. Conklin, a geneticist at the Gladstone Institutes in San Francisco, California, had been trying to work out how variations in DNA affect various...